Zinc is a nutrient that people need to stay healthy. Zinc is found in cells throughout the body. It helps the immune system fight off invading bacteria and viruses. The body also needs zinc to make proteins and DNA, the genetic material in all cells. Zinc also helps wounds heal and is important for proper senses of taste and smell.

How zinc is related to insulin?
Since Zn plays a clear role in the synthesis, storage and secretion of insulin as well as conformational integrity of insulin in the hexametric form, the decreased Zn, which affects the ability of the islet cell to produce and secrete insulin, might then compound the problem, particularly in Type 2 diabetes.

The risk of developing type 2 diabetes increases with age, obesity and lack of physical activity. Insulin resistance is a fundamental aspect of the etiology of type 2 diabetes. Insulin resistance has been shown to be associated with atherosclerosis, dyslipidemia, glucose intolerance, hyperuricemia, hypertension and polycystic ovary syndrome. The mineral zinc plays a key role in the synthesis and action of insulin, both physiologically and in diabetes mellitus. Zinc seems to stimulate insulin action and insulin receptor tyrosine kinase activity.

Int J Infect Dis. 2020 Nov; 100: 343–349.
Published online 2020 Sep 10. doi: 10.1016/j.ijid.2020.09.014
PMCID: PMC7482607
PMID: 32920234
COVID-19: Poor outcomes in patients with zinc deficiency

Zinc supplementation for the prevention of type 2 diabetes mellitus in adults with insulin resistance.

Zinc status, insulin resistance and glycoxidative stress in elderly subjects with type 2 diabetes mellitus.

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